Table 1 Clinicopathological factors of patients with and without brain metastasis.
Characteristics | No brain metastasis N = 58,863 | Brain metastasis N = 368 | X2 | P value |
|---|---|---|---|---|
Age | 17.222 | < 0.001 | ||
≤ 60 years | 17,949 (99.2%) | 149 (0.8%) | ||
> 60 years | 40,914 (99.5%) | 219 (0.5%) | ||
Sex | 20.222 | < 0.001 | ||
Male | 35,624 (99.3%) | 265 (0.7%) | ||
Female | 23,239 (99.6%) | 103 (0.4%) | ||
Race | 18.324 | < 0.001 | ||
Caucasian | 41,697 (99.3%) | 298 (0.7%) | ||
African American | 7746 (99.6%) | 30 (0.4%) | ||
Others | 9420 (99.6%) | 40 (0.4%) | ||
Tumor site | 101.328 | < 0.001 | ||
Cardia | 17,400 (99.0%) | 182 (1.0%) | ||
Antrum | 9642(99.8%) | 16 (0.2%) | ||
Body | 6649 (99.6%) | 24 (0.4%) | ||
Fundus | 3066 (99.4%) | 19 (0.6%) | ||
Greater | 2635 (99.6%) | 11 (0.4%) | ||
Lesser | 4287 (99.6%) | 16 (0.4%) | ||
Pylorus | 1364 (99.9%) | 2 (0.1%) | ||
Not specified | 13,820 (99.3%) | 98 (0.7%) | ||
Histological type | 6.884 | 0.142 | ||
Adenocarcinoma | 41,251 (99.4%) | 267 (0.6%) | ||
Mucinous | 794 (99.7%) | 2 (0.3%) | ||
Papillary | 187 (98.9%) | 2 (1.1%) | ||
Signet ring cell | 8938 (99.3%) | 62 (0.7%) | ||
Other | 7693 (99.5%) | 35 (0.5%) | ||
Grade | 35.421 | < 0.001 | ||
Grade I | 4885 (99.94%) | 3 (0.06%) | ||
Grade II | 11,760 (99.4%) | 69 (0.6%) | ||
Grade III | 26,940 (99.4%) | 169 (0.6%) | ||
Grade IV | 914 (99.1%) | 8 (0.9%) | ||
Unknown | 14,364 (99.2%) | 119 (0.8%) | ||
Tumor size | 115.675 | < 0.001 | ||
≤ 5 cm | 23,475 (99.7%) | 80 (0.3%) | ||
> 5 cm | 12,649 (99.6%) | 45 (0.4%) | ||
Others | 22,739 (98.9%) | 243 (1.1%) | ||
T stage | 226.769 | < 0.001 | ||
T1 | 14,042 (99.6%) | 53 (0.4%) | ||
T2 | 6545 (99.8%) | 12 (0.2%) | ||
T3 | 13,203 (99.7%) | 39 (0.3%) | ||
T4 | 9209 (99.6%) | 37 (0.4%) | ||
Unknown | 15,864 (98.6%) | 227 (1.4%) | ||
N stage | 124.920 | < 0.001 | ||
No | 30,633 (99.6%) | 118 (0.4%) | ||
N1 | 11,769 (99.2%) | 100 (0.8%) | ||
N2 | 4179 (99.7%) | 11 (0.3%) | ||
N3 | 3998 (99.4%) | 23 (0.6%) | ||
Unknown | 8284 (98.6%) | 116 (1.4%) | ||
Surgery | 244.251 | < 0.001 | ||
No | 31,351 (98.1%) | 346 (1.1%) | ||
Yes | 27,512 (99.92%) | 22 (0.08%) | ||
Bone metastasis | 720.662 | < 0.001 | ||
No | 56,509 (99.6%) | 250 (0.4%) | ||
Yes | 2353 (95.2%) | 118 (4.8%) | ||
Liver metastasis | 184.186 | < 0.001 | ||
No | 50,302 (99.6%) | 222 (0.4%) | ||
Yes | 8561 (98.3%) | 146 (1.7%) | ||
Lung metastasis | 757.173 | < 0.001 | ||
No | 56,156 (99.6%) | 238 (0.4%) | ||
Yes | 2707 (95.4%) | 130 (4.6%) | ||
Income | 2.131 | 0.345 | ||
Less than 50 k | 7872 (99.4%) | 44 (0.6%) | ||
50–75 k | 32,012 (99.3%) | 214 (0.7%) | ||
More than 75 k | 18,979 (99.4%) | 110 (0.6%) |
