Table 3 Odds ratios of mortality (with 95% confidence interval).

From: Prevalence and prognostic value of neurological affections in hospitalized patients with moderate to severe COVID-19 based on objective assessments

Predictor

95% CI

OR

Lower

Upper

p-value

MRS

3.13

1.66

6.88

0.00058

Number of comorbidities

1.40

0.86

2.22

0.17

Male sex

2.60

0.75

13.63

0.14

Age

1.04

1.01

1.09

0.012

Lymphocytes (adm)

1.01

0.04

1.18

0.93

C-reactive protein (adm)

1.13

1.06

1.18

0.00014

Urea concentration (adm)

1.02

1.00

1.03

0.0053

Oxygen saturation (adm)

0.83

0.74

0.91

 < 0.0001

Respiratory rate (adm)

1.05

0.94

1.16

0.34

Radiographic infiltrates (adm)

2.17

0.68

8.84

0.20

Oxygen therapy (adm)

3.20

1.09

9.76

0.034#

Sedation

50.60

10.65

324.94

 < 0.0001

WHO score ≥ 5 (unsedated)

4.29

0.82

42.73

0.086

WHO score ≥ 5 (all)

11.05

2.58

103.09

0.00044

WHO score ≥ 6 (unsedated)

33.37

6.22

225.40

 < 0.0001

WHO score ≥ 6

87.94

21.75

513.58

 < 0.0001

WHO score ≥ 7 (all)

97.93

17.57

1034.42

 < 0.0001

PNS affection (unsedated)

0.95

0.20

5.63

0.95

PNS affection (all)

1.46

0.44

6.10

0.55

CNS affection (unsedated)

2.22

0.45

10.92

0.31

CNS affection (all)

2.16

0.67

6.98

0.19

NCS pathology (unsedated)

1.51

0.27

15.42

0.66

NCS pathology (all)

3.11

0.68

29.69

0.14

MEP pathology (unsedated)

0.87

0.08

5.61

0.89

MEP pathology (all)

2.56

0.60

12.66

0.19

SSEP pathology (unsedated)

6.10

1.01

65.13

0.049#

SSEP pathology (all)

5.65

1.26

33.86

0.023#

SSR pathology (unsedated)

1.05

0.10

5.64

0.96

SSR pathology (all)

4.15

1.21

14.75

0.024

BR pathology (unsedated)

4.34

0.70

21.78

0.11

BR pathology (all)

13.87

4.06

53.82

 < 0.0001

  1. All scores refer to the time of examination if not indicated otherwise. Number of comorbidities were defined according to the extended Charlson comorbidity index26. No results for the Glasgow coma scale19 at admission are displayed because all patients achieved the highest possible score. p-values < 0.05 are in boldface. #indicates that significance was lost after controlling for age and sex.
  2. CI, Confidence interval; adm, Score refers to the time of admission to the hospital; MRS, Modified Rankin Scale; WHO score, WHO clinical progression scale; PNS, Peripheral nervous system; CNS, Central nervous system; NCS, Nerve conduction studies; MEP, Motor evoked potentials; SSEP, Somatosensory evoked potentials; SSR, Sympathetic skin response; BR, Blink reflex.
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