Figure 6 | Scientific Reports

Figure 6

From: Formulation of lipid polymer hybrid nanoparticles of the phytochemical Fisetin and its in vivo assessment against severe acute pancreatitis

Figure 6

Effect of different experimental groups on l-arginine (l-arg) induced severe acute pancreatitis (SAP) in rats; (a) Histopathological changes of the pancreatic tissue stained with H&E. Black arrows, arrow heads and curved arrow reveal interstitial tissue edema, congested blood vessels and periductal inflammatory cell infiltration, respectively. Letters Ex and En show the exocrine and endocrine parts (Islets of Langerhans) of the pancreas, respectively. (b) Pancreas necrosis score, (c) Pancreas hemorrhage score, (d) Pancreas inflammation score, (e) Serum Amylase, (f) Serum Lipase. Data are represented as median and interquartile change in (b–d) and mean ± SEM in (e,f) (n = 6). *,**,*** significantly difference at p-value < 0.05, 0.01 and 0.001, respectively, using Kruskal–Wallis test followed by Dunn multiple comparison test (b–d) and One-way ANOVA followed by Tukey’s multiple comparisons test (e,f). (Magnification X: 400, bar = 25 μm).

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