Table 2 Correlation between clinicopathologic parameters, DMFS and DFS.

Parameters	No^a	Stage II				No^a	Stage III
Parameters	No^a	DMFS (%)	p value*	DFS (%)	p value*	No^a	DMFS (%)	p value*	DFS (%)	p value*
	459	68		66		410	54		53
Sex			0.133		0.107			0.945		0.986
Female	212	72		71		189	54		53
Male	247	64		63		221	55		53
Age			< 0.001		< 0.001			< 0.001		< 0.001
< 65	194	80		79		194	66		65
≥ 65	265	59		57		216	44		43
pT stage			NA		NA			< 0.001		< 0.001
pT1-2	1	0		0		32	88		88
pT3-4	458	68		67		377	52		50
Tumor location			0.454		0.583			0.052		0.085
Distal colon	245	69		68		221	58		57
Proximal colon	212	66		65		186	50		50
Tumor differentiation			0.214		0.232			0.67		0.688
Well to moderate	448	68		67		402	54		53
Poor	5	40		40		2	50		50
Lymphovascular invasion			0.010		0.005			0.039		0.021
Absent	309	71		70		114	62		62
Present	147	61		59		294	51		50
Perineural invasion			0.055		0.033			0.008		0.002
Absent	326	71		70		210	61		61
Present	128	62		59		198	48		46
TLR1-N248			0.34		0.36			0.019		0.026
WT	82	62		61		62	68		66
Variant	377	69		68		348	52		51
TLR2 promoter (− 196 to − 174)			0.747		0.806			0.732		0.503
WT	265	66		66		229	53		51
Variant	193	69		67		180	56		56

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