Figure 3

Effectiveness of InterVar (I), TAPES (T), Psi-Variant (P), and their combinations in detecting candidate variants in ASD genes. (A) Positive predictive value (PPV) of detecting candidate variants in SFARI 1 and all SFARI genes. (B) Odds Ratios (ORs) of detecting candidate variants in SFARI 1 and all SFARI genes. (C) Diagnostic yield (%) achieved by the different tool combinations for detecting candidate variants in SFARI 1 and all SFARI genes.