Figure 3

Comparison between the total number of drugs for which the 25 adverse events (AEs) most impacted by the pandemic were disproportionally reported before the Coronavirus disease 2019 (COVID-19) pandemic up to 31/Dec/2019 (light blue) and the corresponding number of drugs using all reports up to 31/Dec/2021 (orange) and excluding entries solely registering COVID-19 vaccines (dark blue).