Figure 3 | Scientific Reports

Figure 3

From: SIGNET: transcriptome-wide causal inference for gene regulatory networks

Figure 3

IPA validation of the top subnetwork constructed for healthy lung tissues. (a) Top ten significant Ingenuity canonical pathways, with IEC abbreviated for Intestinal Epithelial Cells, RA for Rheumatoid Arthritis, MTC for Macrophages and T Helper Cells, and COPD for Chronic Obstructive Pulmonary Disease. (b) The five most significant types of diseases and functions identified by IPA, with each type shown as the top ten significant diseases/functions.

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