Figure 2
From: Engineered CHO cells as a novel AAV production platform for gene therapy delivery
GFP expression and rAAV9-GFP production from stable CHO cell pools. (a) Mean GFP expression from rHSV1-GFP infected stable cell pools (MOI = 10) from total five time points post-infection. Data were analyzed with one-way ANOVA and expressed as mean with SEM. The ns means non-significant,****p-value < 0.0001, ***p = 0.0004, *p = 0.016. (b) qPCR rAAV9-GFP titers (vg/mL) from supernatant of infected stable cell pools 24 hpi using an MOI of 1:1 of rHSV1-GFP to rHSV-AAV9 vectors. ****p-value < 0.0001. All samples were tested in duplicate, and data were tested with one-way ANOVA, and data presented as mean ± standard deviation (SD).
