Figure 4
From: Engineered CHO cells as a novel AAV production platform for gene therapy delivery
Evaluation of production of rAAV6.2-GFP in top eight CHO-HVEM clones. (a) Cell viability plots post-rHSV-1 vectors co-infection. (b) Viable cell density plots post-rHSV-1 vectors co-infection. (c) The rAAV6.2-GFP titers using an MOI of 1:1. Ns means non-significant, **p = 0.0015. (d) The rAAV6.2-GFP production in CHO–HV–C1 and CHO–HV–C62 clones using different MOIs. *p = 0.051. (e) Production of rAAV8-GFP and rAAV9-GFP in CHO–HV–C1 cells at 24 and 30 hpi.
