Figure 6 | Scientific Reports

Figure 6

From: DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle

Figure 6The alt text for this image may have been generated using AI.

Protein expression levels and methylation ratios of enzymes in functional or metabolic pathways in the liver. (a) coagulation system, (b) complement system (classical and lectin pathways), (c) urea cycle, (d) CYP450-related drug metabolism, (e) tryptophan metabolism. #represents proteins encoded by highly methylated genes in both liver and muscle but differ significantly between the liver and skeletal muscle in both methylation and protein expression. See Fig. 5 for detailed key to plots of expression levels versus methylation ratios for encoding genes. A representative pattern for liver-dominant DM-DEPs is provided.

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