Table 1 Characteristics of the 75 patients whose metabolome abundances are described. LOS = Length of Stay; APACHE II = Acute Physiology and Chronic Health Evaluation Score; SOFA = Sequentional Organ Failure Assessment; RRT = Renal Replacement Therapy; NMBA = Neuromuscular Blockade administration. Data are mean (95% confidence intervals), except for # indicating median with range.
From: The metabolic effects of intermittent versus continuous feeding in critically ill patients
Intermittent Feeding (n = 40) | Continuous Feeding (n = 35) | |
|---|---|---|
Age, y | 55(50.0–60.0) | 61 (55–67) |
Male, No. (%) ¥ | 11 (27.5) | 9 (25.7) |
LOS prior to ICU admission, d # | 0.0 (0–15) | 0.0 (0–13) |
Period ventilated, d # | 11 (2–48) | 8 (2–41) |
ICU LOS, d# | 16 (3–93) | 17 (3–52) |
Hospital LOS, d# | 27 (4–183) | 32 (4–102) |
APACHE II score | 21 (19–24) | 20 (17–22) |
SOFA score on admission | 10 (9–11) | 11 (10–12) |
ICU survival, No. (%) | 28 (70) | 29 (83) |
Hospital survival, No. (%) | 21 (52.5) | 28 (80) |
RRT, No. (%) | 16 (40) | 12 (34) |
NMBA use, d# | 0 (0–8) | 1 (0–6) |
Hydrocortisone dose, mg total by day 10 | 0 (0–2700) | 0 (0–3200) |
Gastro-protection, d# | 9 (0–11) | 10 (0–11) |
Vasopressors support, d# | 4 (0–11) | 5 (0–22) |
Sedation use, d# | 7 (2–11) | 6 (0–11) |
Propofol dose by day 10, g | 21.1 (15.2–27.1) | 23.0 (16.4–29.5) |
Admission diagnosis, No. (%) | ||
Sepsis | 13 (32.5) | 14 (40) |
Cardiogenic shock | 9 (22.5) | 8 (22.9) |
Trauma | 5 (12.5) | 7 (20.0) |
Respiratory failure | 5 (12.5) | 1 (2.9) |
Intracranial haemorrhage | 2 (5.0) | 1 (2.9) |
Acute liver failure | 2 (5.0) | 2 (5.7) |
Acute kidney Injury | 2 (5.0) | 1 (2.9) |
Drug overdose | 1 (2.5) | 0 (0.0) |
Emergency surgery | 1 (2.5) | 1 (2.9) |
Cerebrovascular accident | 0 (0.0) | 0 (0.0) |
Comorbidities, No. (%) | ||
Hypertension | 9 (22.5) | 4 (11.4) |
Chronic respiratory diseases | 9 (22.5) | 11 (31.4) |
Diabetes Mellitus | 8(20.0) | 7 (20.0) |
Ischemic heart disease | 8 (20.0) | 10 (28.6) |
Psychiatric diseases | 6 (15.0) | 5(14.3) |
Renal impairment | 2 (5.0) | 5 (14.3) |
Obesity | 4 (10.0) | 1 (2.9) |
Liver cirrhosis | 3 (7.5) | 3 (8.6) |
Haem-oncological disease | 3 (7.5) | 1 (2.9) |
Thyroid disease | 2 (5.0) | 0 (0.0) |
Crohn’s disease | 0 (0.0) | 1 (2.9) |
Previous CVA | 1 (2.5) | 1 (2.9) |
Chronic Pancreatitis | 1 (2.5) | 0 (0.0) |
