Table 1 Patient characteristics at diagnosis.

From: Comparison of the prognostic impact of IPI and PIT in peripheral T-cell lymphoma in real-world practice with a large elderly population

 

All patients (N = 113)

Age, years—median, range

67 (16–88)

Age > 60 years—n (%)

75 (66.4)

Male—n (%)

75 (66.4)

Diagnosis—n (%)

 PTCL-NOS

78 (69.0)

 ALK-positive ALCL

9 (8.0)

 ALK-negative ALCL

5 (4.4)

 AITL

15 (13.3)

 EATL

5 (4.4)

 HSTL

1 (0.9)

ECOG PS ≥ 2—n (%)

33 (29.2)

B symptoms—n (%)

52 (46.0)

Elevated LDH (> ULN)—n (%)

71 (62.8)

Ann Arbor Stage III/IV—n (%)

90 (79.6)

Extranodal sites ≥ 2—n (%)

29 (25.7)

BM involvement—n (%)

27 (23.9)

IPI—n (%)

 Low (0, 1)

23 (20.4)

 Low-intermediate (2)

22 (19.5)

 High-intermediate (3)

42 (37.2)

 High (4, 5)

26 (23.0)

PIT—n (%)

 Group 1 (0)

12 (10.6)

 Group 2 (1)

32 (28.3)

 Group 3 (2)

41 (36.3)

 Group 4 (3, 4)

28 (24.8)

First treatment

 CHOP

59 (52.2)

 THP-COP

49 (43.4)

 Other

5 (4.4)

Upfront auto-SCT

12 (10.6)

  1. AITL angioimmunoblastic T-cell lymphoma, ALCL anaplastic large cell lymphoma, ALK anaplastic lymphoma kinase, BM bone marrow, EATL enteropathy-associated T-cell lymphoma, ECOG PS Eastern Cooperative Oncology Group performance status, HSTL hepatosplenic T-cell lymphoma, IPI International Prognostic Index, LDH lactate dehydrogenase, PIT Prognostic Index for PTCL-U, PTCL-NOS peripheral T-cell lymphoma, not otherwise specified, ULN upper limit of normal.