Figure 1
From: Collagen type XIV is proportionally lower in the lung tissue of patients with IPF
Gene expression profile of COL14A1 in IPF and non-IPF lungs. A) COL14A1 expression in healthy lungs (data reconstructed from single-cell RNA-sequencing data obtained from Sikkema et al.14. B) COL14A1 expression in IPF and non-IPF lungs (reconstructed from single-cell RNA-sequencing data obtained from Adams et al.15. C) Comparison of COL14A1 counts in IPF and non-IPF lungs across relevant cell types: alveolar type 1 (AT1) and type 2 (AT2), bronchial epithelial cells (BE), fibroblasts (Fb), myofibroblasts (MyF) and smooth muscle cells (SMC). Data are represented as median ± 95% confidence interval. Applied statistical test: Mann–Whitney U test. n = 28 for non-IPF, n = 32 for IPF.
