Figure 4
From: High-throughput analysis system of interaction kinetics for data-driven antibody design
Crystal structure of hPD-1 (brown surface) and toripalimab (blue ribbon) (PDBID 6JBT). Hotspot residues (a) and residues that regulate affinity to mPD-1 (b). Orange: hotspot residues for hPD-1 and mPD-1; green: hotspot residues for mPD-1; magenta: residues that regulate affinity to mPD-1.
