Table 4 Relative dose intensity of DOC and RAM in patients with or without baseline anemia and prophylactic G-CSF administration.
Treatment reduction (n, %) | P-value | DOC RDI (%) | P-value | RAM RDI (%) | P-value | |
|---|---|---|---|---|---|---|
Baseline anemia | ||||||
Present (n = 100) | 16 (16.0%) | < 0.01** | 97.8 ± 6.3 | < 0.01** | 93.3 ± 24.0 | 0.18 |
Absent (n = 55) | 24 (43.6%) | 91.8 ± 10.2 | 89.5 ± 26.3 | |||
Prophylactic G-CSF administration | ||||||
Present (n = 106) | 16 (15.1%) | < 0.01** | 97.7 ± 6.4 | < 0.01** | 95.8 ± 19.3 | < 0.01** |
Absent (n = 49) | 24 (49.0%) | 91.2 ± 10.3 | 83.4 ± 32.5 | |||