Table 3 Comparison of absorbed dose in the source organs between conventional method and PMOD.
From: Assessing the applicability of PMOD residence times model for PET image-based radiation dosimetry
Organs | 18F-T807 | 18F-Mefway | ||||||
|---|---|---|---|---|---|---|---|---|
Male (n = 3) | Female (n = 3) | Male (n = 3) | Female (n = 3) | |||||
Conventional | PMOD | Conventional | PMOD | Conventional | PMOD | Conventional | PMOD | |
Adrenals | 16.3 ± 0.3 | 13.0 ± 4.2 | 21.3 ± 0.3 | 17.1 ± 4.6 | 12.6 ± 0.6 | 12.2 ± 0.8 | 15.9 ± 1.7 | 15.6 ± 2.4 |
Brain | 11.2 ± 1.2 | 9.1 ± 0.3 | 14.2 ± 4.5 | 11.5 ± 3.6 | 5.8 ± 0.9 | 5.1 ± 0.8 | 8.6 ± 0.2 | 7.6 ± 0.3 |
Breasts | 8.9 ± 0.4 | 6.3 ± 3.4 | 10.8 ± 0.1 | 8.0 ± 4.0 | 6.0 ± 0.2 | 6.3 ± 0.2 | 8.0 ± 0.2 | 8.3 ± 0.9 |
Gallbladder wall | 29.4 ± 12.6 | 18.7 ± 3.6 | 60.3 ± 20.5 | 65.5 ± 34.0 | 16.8 ± 1.4 | 15.9 ± 1.6 | 20.4 ± 2.4 | 19.7 ± 3.6 |
Lower large intestine wall | 12.2 ± 0.7 | 11.1 ± 6.0 | 13.8 ± 0.6 | 10.7 ± 6.0 | 19.0 ± 0.3 | 20.0 ± 0.5 | 23.2 ± 2.4 | 24.8 ± 2.1 |
Small intestine | 33.5 ± 8.3 | 35.8 ± 0.9 | 29.6 ± 3.6 | 26.9 ± 4.5 | 14.4 ± 0.5 | 14.7 ± 0.9 | 16.7 ± 0.7 | 17.3 ± 0.7 |
Stomach wall | 12.2 ± 0.2 | 9.1 ± 4.6 | 15.1 ± 0.2 | 11.5 ± 5.3 | 9.2 ± 0.1 | 9.5 ± 0.3 | 11.8 ± 0.8 | 12.2 ± 1.3 |
Upper large intestine wall | 15.7 ± 1.2 | 13.8 ± 4.2 | 17.8 ± 0.6 | 14.5 ± 5.4 | 12.5 ± 0.1 | 12.8 ± 0.5 | 15.8 ± 0.1 | 16.5 ± 1.0 |
Heart wall | 20.1 ± 1.4 | 15.3 ± 2.0 | 29.1 ± 0.9 | 19.5 ± 9.8 | 7.4 ± 0.4 | 7.0 ± 0.6 | 12.5 ± 2.3 | 11.6 ± 2.4 |
Kidneys | 26.2 ± 8.6 | 30.6 ± 5.7 | 43.6 ± 11.7 | 38.5 ± 10.6 | 49.5 ± 10.8 | 43.2 ± 7.7 | 33.6 ± 4.7 | 31.2 ± 4.9 |
Liver | 61.6 ± 6.0 | 61.4 ± 7.8 | 100.8 ± 3.9 | 89.3 ± 6.2 | 52.3 ± 10.0 | 42.8 ± 8.5 | 75.4 ± 15.2 | 64.9 ± 19.2 |
Lungs | 41.3 ± 7.9 | 35.2 ± 3.8 | 57.7 ± 3.6 | 50.9 ± 2.4 | 13.2 ± 1.9 | 11.8 ± 1.9 | 22.8 ± 2.5 | 19.6 ± 2.5 |
Muscle | 9.9 ± 0.3 | 7.5 ± 4.3 | 11.7 ± 0.1 | 8.8 ± 4.7 | 9.7 ± 0.2 | 10.2 ± 0.3 | 12.0 ± 0.1 | 12.6 ± 0.7 |
Ovaries | – | – | 14.8 ± 0.6 | 11.7 ± 5.9 | – | 22.9 ± 2.2 | 24.4 ± 1.9 | |
Pancreas | 15.3 ± 0.1 | 12.1 ± 4.6 | 20.0 ± 0.3 | 15.9 ± 5.3 | 11.9 ± 0.4 | 11.7 ± 0.6 | 15.1 ± 1.5 | 15.1 ± 2.2 |
Osteogenic cells | 17.7 ± 0.8 | 13.4 ± 6.0 | 23.3 ± 1.5 | 17.8 ± 7.6 | 12.9 ± 0.7 | 13.5 ± 0.6 | 17.5 ± 0.5 | 18.3 ± 1.3 |
Skin | 7.3 ± 0.3 | 5.1 ± 3.4 | 8.4 ± 0.1 | 6.1 ± 3.8 | 6.2 ± 0.2 | 6.6 ± 0.2 | 7.7 ± 0.2 | 8.2 ± 0.6 |
Spleen | 11.2 ± 0.3 | 8.2 ± 4.5 | 14.0 ± 0.4 | 10.6 ± 5.2 | 8.9 ± 0.2 | 9.2 ± 0.2 | 11.0 ± 0.8 | 11.5 ± 1.1 |
Testes | 8.4 ± 0.5 | 9.6 ± 0.5 | – | – | 13.6 ± 0.4 | 14.4 ± 0.3 | – | – |
Thymus | 10.7 ± 0.6 | 7.4 ± 4.2 | 12.9 ± 0.1 | 9.5 ± 5.1 | 7.0 ± 0.4 | 7.4 ± 0.2 | 9.4 ± 0.7 | 9.9 ± 1.0 |
Thyroid | 9.1 ± 0.5 | 5.9 ± 4.4 | 9.7 ± 0.1 | 6.8 ± 4.7 | 6.4 ± 0.4 | 6.9 ± 0.2 | 7.6 ± 0.4 | 8.3 ± 0.7 |
Urinary bladder wall | 32.2 ± 13.4 | 61.2 ± 32.5 | 51.8 ± 23.1 | 56.7 ± 23.5 | 410 ± 6.0 | 421.3 ± 11.5 | 532.0 ± 107.8 | 562.3 ± 95.9 |
Uterus | 15.4 ± 1.2 | 12.6 ± 6.3 | 36.73 ± 5.05 | 38.97 ± 4.44 | ||||
Effective dose | ||||||||
(μSv/MBq) | 19.2 ± 0.4 | 21.1 ± 7.3 | 25.7 ± 0.8 | 22.1 ± 4.3 | 34.9 ± 0.4 | 35.2 ± 1.15 | 45.6 ± 4.9 | 46.8 ± 4.9 |
