Figure 7 | Scientific Reports

Figure 7

From: The common H232 STING allele shows impaired activities in DNA sensing, susceptibility to viral infection, and in monocyte cell function, while the HAQ variant possesses wild-type properties

Figure 7

IFNβ secretion in CT26 cell lines induced by viral infection. (A) CT26 cell derivatives (R232, HAQ, H232 and SKO) were infected at MOI 10 pfu/cell with wild type HSV-1 and the supernatants were collected 10 h and 48 h post infection to dose interferon beta. The statistical analysis was performed by student’s t test using not infected cells as reference. (B) The same experiment was performed using a different DNA-based virus, MVA at MOI 1 and 5. The statistical analysis was performed by student’s t test using NI of each allele as reference.

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