Table 1 Patient characteristics and data trends.
Case | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
Age | 67 | 66 | 74 | 70 | 55 | 54 |
Sex | M | M | M | M | F | M |
Etiology | NICM | Ischemic | Ischemic | NICM | NICM | NICM |
BMI | 28.3 | 29 | 33.9 | 31.25 | 33 | 29.7 |
Device duration, days | 27 | 27 | 22 | 14 | 3 | 6 |
Survival after transplant (days) | 562 | 547 | 466 | 291 | 571 | 485 |
Blood group | O | O | A | B | O | O |
Diabetic | N | Y | N | N | N | N |
Hemoglobin A1c (%) | 5.9 | 8 | 6.2 | 5.7 | 5.8 | 6 |
LVEF pre-impella (%) | 14 | 13 | 26 | 10 | 18 | 24 |
Historic lab and imaging data (1 year prior to admission) | ||||||
LVEF (%) | 16 | 15 | 10 | 18 | 18 | 21 |
Creatinine g/dL | 1.26 | 3 | 1.2 | 1.64 | 1.49 | 1.58 |
GFR | 56 | < 15 | 55 | 24 | 46 | 49 |
Kidney size (cm) | 9.8 R / 11 L | 11.5 R / 12 L | 12.5 R / 12.8 L | 11.7 R / 10.8 L | 10.5 R / 10.5 L | 12.5 R / 12.1 L |
Pre-impella data (most recent data before Impella placement) | ||||||
MAP | 61 | 68 | 73 | 90 | 102 | 73 |
RA | 12 | 10 | 2 | 12 | 15 | 15 |
PA | 54/23 | 40/22 | 72/30 | 63/32 | 75/37 | 45/25 |
PA mean | 33 | 28 | 44 | 42 | 50 | 32 |
PCWP | 30 | 14 | 30 | 35 | 32 | 25 |
SVO2 prior to impella (%) | 35% | 60% | 67% | 55% | 52% | 58% |
Fick CO | 4.20 | 2.5 | 5.7 | 3.07 | 2.5 | 3.5 |
Fick CI pre-impella | 1.90 | 1.4 | 2.4 | 1.41 | 1.2 | 1.5 |
CPO | 0.57 | 0.38 | 0.92 | 0.61 | 0.57 | 0.57 |
PAPi | 2.58 | 1.8 | 21 | 2.58 | 2.5 | 1.33 |
CVP/PCWP | 0.40 | 0.71 | 0.07 | 0.34 | 0.47 | 0.60 |
PVR | 0.71 | 5.60 | 2.46 | 2.28 | 7.20 | 2.00 |
SVR | 933 | 1856 | 996 | 2033 | 2784 | 1326 |
VIS pre-impella | 10.00 | 7.5 | 4.8 | 2.5 | 2.5 | 8.7 |
Hematocrit | 30.4 | 25.4 | 33.5 | 39.1 | 34.3 | 30.3 |
Pre-Impella Cr | 2.11 | 2.37 | 1.64 | 2.63 | 1.6 | 2.08 |
Pre-Impella GFR | 32 | 28 | 41 | 24 | 41 | 35 |
Pre-Impella CKD Stage | 3 | 4 | 3 | 4 | 3 | 3 |
Pre-transplant data (most recent data before transplantation) | ||||||
MAP | 73 | 88 | 76 | 78 | 72 | 74 |
SVO2 prior to transplant (%) | 55% | 63% | 55% | 67% | 64% | 65% |
Fick CO | 3.48 | 5.93 | 9.7 | 5.1 | 4.50 | 5.5 |
Fick CI | 1.83 | 2.85 | 4.2 | 2.4 | 2.20 | 2.5 |
CPO | 0.56 | 1.16 | 1.63 | 0.88 | 0.72 | 0.90 |
Hematocrit | 29.2 | 26.8 | 31.2 | 38.9 | 36.2 | 29.1 |
Pre-TxpCr | 1.92 | 0.72 | 1.5 | 2.3 | 1.36 | 1.45 |
Pre-Txp GFR | 35 | 90 | 44 | 32 | 51 | 63 |
Pre-Txp CKD stage | 3 | 1 | 3 | 3 | 3 | 2 |
Average LDH | 388 | 166 | 253 | 245 | 315 | 117 |
VIS pre-transplant | 10.00 | 5 | 3.75 | 2.5 | 2.5 | 5 |
Peri-transplant and discharge data | ||||||
UNOS status at transplant | 2 | 2 | 2 | 2 | 2 | 1e (RV Failure) |
Cardiopulmonary bypass time (min) | 124 | 155 | 168 | 191 | 145 | 188 |
Cold ischemic time (minutes) | 190 | 191 | 226 | 136 | 219 | 247 |
Discharge creatinine | 1.1 | 1.05 | 1.3 | 1.6 | 0.96 | 1.1 |
Discharge GFR | 69 | 74 | 54 | 42 | 78 | 75 |
Post-txp CKD stage | 2 | 2 | 3 | 3 | 2 | 2 |
Total hospital stay (days) | 49 | 41 | 42 | 22 | 15 | 59 |
Device to transplant time (days) | 27 | 27 | 22 | 15 | 3 | 6 |
ICU LOS Post Txp (days) | 7 | 5 | 5 | 4 | 4 | 3 |
VIS post transplant | 9.12 | 17.3 | 7 | 11.40 | 7.5 | 8 |
