Table 1 Patient characteristics for each time period.
Total (N = 741) (%) | A (N = 217) 2011–2014 | B (N = 293) 2015–2018 | C (N = 231) 2019–2021 | P | |
|---|---|---|---|---|---|
Median age, years (range) | 68 (22–90) | 68 (22–84) | 69 (26–87) | 68 (28–90) | – |
Sex (male/female) | 488/253 (66/34) | 146/71 (67/33) | 192/101 (66/34) | 150/81 (65/35) | 0.86 |
Metastatic/recurrence | 549/192 (74/26) | 159/58 (73/27) | 210/83 (72/28) | 180/51 (78/22) | 0.25 |
HER2 (+/−/unknown) | 121/553/70 (16/75/9) | 21/134/62 (10/61/29) | 55/236/2 (19/80/1) | 45/183/3 (20/79/1) | – |
Brain metastases | 16 (2.2) | 3 (1.4) | 7 (2.4) | 6 (2.6) | 0.63 |
