Figure 4

Analysis of DEGs in HK-2 normoxia compared with hypoxia. (a) Volcano plots of DEGs between the two groups. The cutoff criteria for significant DEGs were p-adjust < 0.05 and |log2(FC)|> 1. The significantly upregulated transcripts and downregulated transcripts are shown in red and blue, respectively. (b) Heatmaps indicating hierarchical clustering of DEGs between HK-2 normoxia and HK-2 hypoxia. The color from green to blue indicates upregulation to downregulation. (c) GO analysis of total DEGs. (d) KEGG enrichment analysis of total DEGs, p-adjust < 0.05.