Table 2 Characteristics of SNPs associated with uridine and their associations with AF.

From: Protective effect of uridine on atrial fibrillation: a Mendelian randomisation study

SNP

Chr:pos

EA/OA

EAF

R2 (%)

F

Uridine

AF (Nielsen et al.)

AF HRC

FinnGen

Beta

SE

p-value

Beta

SE

p-value

Beta

SE

p-value

Beta

SE

p-value

rs2686796

7:48,102,911

T/C

0.4524

6.993

38.435

0.0094

0.0017

1.89E−08

 − 0.0074

0.0067

0.269

 − 0.0142

0.0072

0.048

 − 0.0285

0.0149

0.055

rs532545

1:20,915,172

T/C

0.3065

6.993

38.435

 − 0.0095

0.0017

3.41E−08

0.0158

0.0071

0.026

0.0186

0.0077

0.015

 − 0.0385

0.0183

0.035

rs762669

22:50,943,423

A/G

0.2043

6.303

31.198

0.0112

0.0019

1.21E−09

 − 0.0171

0.0085

0.044

 − 0.0052

0.0096

0.588

 − 0.0137

0.0209

0.512

  1. SNP single-nucleotide polymorphism, Chr chromosome, pos position, EA effect allele, OA other allele, EAF effect allele frequency, R2 percentage of the variation of uridine explained by the SNP, Beta estimate of the effect of the association, SE standard error, F F statistic, AF atrial fibrillation, AF HRC Atrial Fibrillation Haplotype Reference Consortium.
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