Figure 1 | Scientific Reports

Figure 1

From: Phenogrouping and risk stratification of patients undergoing cardiac resynchronization therapy upgrade using topological data analysis

Figure 1

Kaplan–Meier curves depicting the survival of patients upgraded to a CRT-D vs. those upgraded to a CRT-P. Univariable and multivariable Cox proportional hazards models were used to compute hazard ratios with 95% confidence intervals. Besides the type of the implanted device (CRT-D or CRT-P), the multivariable model included the following covariates: age (at the time of the upgrade procedure), sex, history of atrial fibrillation, etiology of heart failure, serum creatinine, left ventricular ejection fraction, angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, and loop diuretics. CI confidence interval, CRT cardiac resynchronization therapy, CRT-D cardiac resynchronization therapy-defibrillator, CRT-P cardiac resynchronization therapy-pacemaker, HR hazard ratio.

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