Table 1 Baseline characteristics between training and test set.

From: Effect of multimodal diagnostic approach using deep learning-based automated detection algorithm for active pulmonary tuberculosis

Variable

Missing, n (%)

Test set n (%) or mean ± SD (N = 2513)

Training set n (%) or mean ± SD (N = 5861)

P-value

Sex

0 (0.0)

  

0.203

Female

 

959 (38.2)

2149 (36.7)

 

Male

 

1554 (61.8)

3712 (63.3)

 

Age (years)

0 (0.0)

67.5 ± 15.4

67.9 ± 15.6

0.274

Mean arterial blood pressure (mmHg)

0 (0.0)

91.0 ± 20.0

91.2 ± 20.7

0.626

Heart rate (min-1)

68 (0.8)

99.9 ± 21.1

100.9 ± 21.7

0.056

Respiratory rate (min-1)

70 (0.8)

19.7 ± 4.3

19.9 ± 4.4

0.094

Body temperature (°C)

57 (0.7)

37.3 ± 1.0

37.3 ± 1.0

0.336

Saturation (%)

94 (1.1)

94.8 ± 5.8

94.7 ± 5.6

0.492

Hypertension

0 (0.0)

1166 (46.4)

2773 (47.3)

0.457

Diabetes

0 (0.0)

726 (28.9)

1743 (29.7)

0.450

AIDS

0 (0.0)

3 (0.1)

31 (0.5)

0.012

Old tuberculosis

0 (0.0)

322 (12.8)

788 (13.4)

0.456

Alcohol history

654 (7.8)

1238 (53.5)

2959 (54.7)

0.330

Never smoker

654 (7.8)

1129 (48.8)

2590 (47.9)

0.494

Cough

0 (0.0)

1109 (44.1)

2492 (42.5)

0.180

Sputum

0 (0.0)

1055 (42.0)

2442 (41.7)

0.807

Fever

0 (0.0)

1366 (54.4)

3143 (53.6)

0.554

Dyspnea

0 (0.0)

1603 (63.8)

3796 (64.8)

0.405

Chest pain

0 (0.0)

458 (18.2)

1057 (18.0)

0.860

Hemoptysis

0 (0.0)

337 (13.4)

827 (14.1)

0.416

Anorexia

0 (0.0)

122 (4.9)

265 (4.5)

0.542

General weakness

0 (0.0)

238 (9.5)

552 (9.4)

0.972

Sweating

0 (0.0)

10 (0.4)

22 (0.4)

1.000

Weight loss

0 (0.0)

17 (0.7)

51 (0.9)

0.440

Body mass index (kg/m2)

4485 (53.6)

22.2 ± 3.9

22.2 ± 4.1

0.957

Albumin (g/dL)

18 (0.2)

3.3 ± 0.6

3.3 ± 0.6

0.813

High density lipoprotein (mg/dL)

7566 (90.4)

36.4 ± 13.3

35.3 ± 13.8

0.269

Low density lipoprotein (mg/dL)

7729 (92.3)

73.0 ± 35.7

77.7 ± 39.7

0.163

Serum sodium (mmol/L)

11 (0.1)

137.3 ± 4.6

137.4 ± 4.6

0.454

Serum potassium (mmol/L)

10 (0.1)

4.2 ± 0.5

4.2 ± 0.5

0.957

Serum chloride (mmol/L)

12 (0.1)

100.6 ± 5.0

100.8 ± 4.9

0.218

Smear microscopy

0 (0.0)

  

0.675

Negative

 

2459 (97.9)

5745 (98.0)

 

Positive

 

54 (2.1)

116 (2.0)

 

Polymerase chain reactiona

6222 (74.3)

  

0.506

Negative

 

609 (99.2)

1529 (99.5)

 

Positive

 

5 (0.8)

9 (0.6)

 

Chest radiography

0 (0.0)

  

0.763

Negative

 

2500 (99.5)

5840 (99.6)

 

Positive

 

13 (0.5)

21 (0.4)

 

Chest computed tomography

980 (23.6)

  

0.911

Negative

 

1780 (92.6)

4154 (92.9)

 

Positive

 

142 (7.4)

318 (7.1)

 

TB screening score by DLAD

0 (0.0)

19.8 ± 22.5

19.3 ± 22.4

0.327

  1. aPolymerase chain reaction (Gene Xpert MTB/RIF).
  2. SD: Standard Deviation, AIDS: Acquired Immune Deficiency Syndrome, TB: tuberculosis, DLAD: Deep Learning-based Automated Detection algorithm.