Figure 7 | Scientific Reports

Figure 7

From: KTt-45, a T-type calcium channel blocker, acts as an anticancer agent by inducing apoptosis on HeLa cervical cancer cell line

Figure 7

The autophagic markers’ staining of HeLa cells treated with KTt-45 at 48 h. (A) MDC staining results of control untreated (0.1% (v/v) DMSO), KTt-45-treated (37.4 μM), rapamycin-treated (40 μM), and chloroquine-treated (25 μM) cells; Columns (1) and (2) display images of cells (bright field) and MDC’s fluorescence (blue field). (B) LC3-staining results of control untreated (0.1% (v/v) DMSO), KTt-45-treated (37.4 μM), and chloroquine-treated (25 μM) cells; Columns (1), (2), (3), and (4) display images of cells (bright field), cell nuclei (blue field), accumulated LC3 signals (green field), and merging (blue amd green field) respectively. The red arrows point vacuole-containing cells. The yellow arrows point shrunken cells. The scale bars indicate 50 μm.

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