Table 1 Baseline demographics and clinical patient characteristics for the subgroup of deceased patients.

From: Absence of COVID-19 associated mucormycosis in a tertiary intensive care unit in the Netherlands

 

Deceased COVID-19 patients in the ICU

Number of patients

89

Sex—Male (%)

69 (78)

Age—year [IQR]

68.5 [60.0–73.0]

BMI—kg/m2 [IQR]

27.3 [24.7–31.2]

Smoking—Yes/Former (%)

30 (57)

Asthma—Yes (%)

6 (7)

COPD—Yes (%)

4 (5)

Interstitial lung disease—Yes (%)

1 (1)

Active solid malignancy—Yes (%)

5 (6)

Active hematological malignancy—Yes (%)

10 (11)

Diabetes—Yes (%)

29 (33)

Probable CAPA—Yes (%)

16 (18)

EORTC host factor—Yes (%)

32 (36)

Number of EORTC host factors (%)

 0

57 (64)

 1

17 (19)

 2

7 (8)

 3

6 (7)

 4

2 (2)

Cumulative amount of corticosteroids—mg [IQR]

500 [400–1172]

Median amount of steroids per day—mg [IQR]

42.6 [24.5–57.7]

IL-6 receptor inhibitor—Yes (%)

10 (11)

Antifungal therapy—Yes (%)

26 (29)

Duration antifungal therapy—Days [IQR]

4 [3–8]

Time in ICU—Days [IQR]

19 [15–30]

SOFA score [IQR]

8 [7–10]

CT severity score [IQR]

24 [21–25]

PaO2/FiO2 ratio—mmHg [IQR]

92.7 [70.5–117.3]

Number of BAL per patient—median [IQR]

2 [1, 2]

Mono organ failure—Yes (%)

47 (53)

Autopsy—Yes (%)

12 (14)

Time between BAL and death—Days [IQR]

5 [4–9]

  1. Continuous data are described as median with interquartile range.
  2. BMI, body mass index; BAL , Broncho-alveolar lavage; CAPA, COVID-19 Associated Pulmonary Aspergillosis; COPD, chronic obstructive pulmonary disease; CT, computed tomography; EORTC, European Organization for Research and Treatment of Cancer; ICU, intensive care unit; IL-6, Interleukin-6; IQR, inter quartile range; SOFA, sequential organ failure assessment.