Table 2 Number of regions of interest scored per component and HNF4α isoform.

From: Differential spatial distribution of HNF4α isoforms during dysplastic progression of intraductal papillary mucinous neoplasms of the pancreas

Component

Isoform

Pan-promoter HNF4α (n = 55)

HNF4α P1 (n = 31)

HNF4α P2 (n = 29)

Acini

84

39

39

Intercalated ducts

84

39

39

Intralobular ducts

84

38

38

Large ducts

42

21

22

Peribiliary glands

39

20

19

ADM

69

32

33

Low-grade IPMN, surface

105

58

58

Low-grade IPMN, base

109

62

62

Low-grade IPMN, total

214

120

120

High-grade IPMN, surface

81

42

46

High-grade IPMN, base

76

36

38

High-grade IPMN, total

157

78

84

Well-diff INV

24

12

12

Poorly diff INV

15

6

6

  1. ADM: Acinar-to-ductal metaplasia; IPMN: Intraductal papillary mucinous neoplasm; Well diff INV: Well-differentiated invasive adenocarcinoma; Poorly diff INV: Poorly differentiated invasive adenocarcinoma.
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