Figure 3
(Left) Anatomic 1H image of a PDAC-implanted mouse, showing among other tissues the kidney, bladder and tumor. (Right) DMI ME-SSFP (uniform sampling) and CSI-SSFP (weighted sampling) data collected at the indicated times after the injection of [6,6′-2H2]-glucose, shown overlaid on the 1H anatomic images. Lactate is present only in the tumor, HDO is spread throughout the body but also concentrates slightly inside the tumor, glucose is visible mostly in the bladder. Notice as well the superior SNR of the HDO and lactate CSI-SSFP images; “granularity” in the ME-SSFP images may be influenced by the higher noise in these experiments.
