Table 3 Thermal parameters of span 60 and acyclovir in pure form and granules.

From: An industrial procedure for the intestinal permeability enhancement of acyclovir: in-vitro and histological evidence

 

Peak 1

Peak 2

peak 3

Span 60

Peak

mp °C

∆H(J/g)

mp °C

∆H(J/g)

mp °C

∆H(J/g)

mp °C

∆H(J/g)

Pure drug

130.3

145.8

173.9

5.2

257.8

187.4

57.95

86.38

15% span

134.4

86.82

173.4

12.9

253.1

143.6

57.42

10.12

20% span

134.1

62.09

173.4

10.99

252.7

144.2

57.13

16.52

25% span

134.7

54.36

173.5

8.92

255.1

141.5

57.17

11.86

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