Table 3 Differential analysis of inflammatory markers significantly correlated with 180-day mortality.

From: Markers of inflammation predict survival in newly diagnosed cirrhosis: a prospective registry study

Cell marker (NPX)

Deceased within 180 days, (n = 28)

Survived past 180 days, (n = 121)

Ancova

q-value

Mean (SD)

Mean (SD)

Unadjusted p-value

LIF

1.96 (1.27)

1.25 (0.49)

0

0

uPA

11.55 (0.55)

11.20 (0.52)

0

0.0009

IL-8

9.44 (1.53)

8.52 (1.39)

0.0001

0.0016

ENRAGE

4.46 (1.69)

3.33 (0.89)

0.0001

0.0018

TGFa

4.29 (0.72)

3.87 (0.49)

0.0001

0.0024

IL15-RA

3.01 (0.78)

2.61 (0.42)

0.0003

0.0049

IL12-B

6.29 (1.28)

6.95 (1.06)

0.0008

0.0103

MCP1

12.55 (0.68)

12.18 (0.56)

0.001

0.0114

CXCL6

10.36 (0.95)

9.90 (0.87)

0.0014

0.0136

HGF

11.21 (1.04)

10.72 (0.84)

0.0015

0.0136

CASP8

4.06 (0.47)

3.77 (0.51)

0.0016

0.0137

CX3CL1

6.10 (0.56)

5.76 (0.57)

0.0018

0.0139

IL10-RB

7.29 (0.27)

7.09 (0.31)

0.002

0.0144

CCL23

10.84 (0.66)

10.36 (0.61)

0.0025

0.0166

FGF19

10.20 (1.52)

9.42 (1.33)

0.0037

0.0226

IL-6

5.71 (1.41)

4.91 (1.19)

0.004

0.0232

TNFSF14

5.85 (0.84)

5.46 (0.79)

0.0046

0.024

ARTN

2.48 (0.89)

2.09 (0.59)

0.0047

0.024

MCP3

2.96 (0.90)

2.46 (0.64)

0.0064

0.031

CCL20

11.46 (1.61)

10.85 (1.33)

0.0096

0.044

  1. ARTN artemin, CASP8 caspase 8, ENRAGE extracellular newly identified receptor for advanced glycation end products binding protein, HGF hepatocyte growth factor, IL interleukin, LIF leukaemia inhibitory factor, MCP1 C–C motif chemokine 2, uPA urokinase plasminogen activator, MCP3 C–C motif chemokine 7, CCL20 C–C motif chemokine 20.
  2. Means of markers are expressed as NPX. N = 149 patients. Significant markers were found adjusting for sex, age, cancer, depression, psychiatric disease, diabetes, heart disease, hypertension and hypercholesterolaemia and their Ancova results are given in terms of unadjusted p-values.