Table 3 Subgroup analyses of associations of height and risk of diabetes.

From: Inverse association between adult height and diabetes risk in a cohort study of Chinese population

Stratified variables

Men (n = 115,766)

Women (n = 95,406)

No

No. of events

HR (95% CI)

No

No. of events

Model 3

HR (95% CI)

Age (year)

 ≥ 20, < 30

15,767

52

0.92 (0.53, 1.62)*

12,755

23

0.89 (0.43, 1.71)*

 ≥ 30, < 40

44,911

430

0.75 (0.63, 0.89)

37,824

114

0.54 (0.37, 0.84)

 ≥ 40, < 50

23,696

613

0.66 (0.57, 0.77)

21,641

176

0.58 (0.44, 0.77)

 ≥ 50, < 60

17,423

939

0.82 (0.72, 0.93)

12,522

282

0.78 (0.62, 0.98)

 ≥ 60, < 70

9641

630

0.82 (0.73, 0.95)

7837

338

0.75 (0.60, 0.93)

 ≥ 70

4328

328

0.90 (0.73, 1.12)

2827

231

1.09 (0.82, 1.44)

BMI (kg/m2)

 < 24

55,993

649

0.75 (0.61, 0.92)

72,515

448

0.70 (0.58, 0.84)

 ≥ 24, < 28

46,035

1445

0.66 (0.56, 0.78)

18,548

481

0.79 (0.65, 0.96)

 ≥ 28

13,738

898

0.97 (0.83, 1.13)

4343

235

0.79 (0.59 1.00)

FPG (mmol/L)

 < 6.1

110,690

1556

0.61 (0.56, 0.68)

93,322

2084

0.64 (0.55, 0.75)

≧ 6.1

5076

1436

0.93 (0.84, 1.03)

673

491

0.84 (0.70, 1.02)

SBP (mmHg)

 < 140

101,290

2139

0.78 (0.72, 0.85)

88,594

762

0.73 (0.63, 0.85)

 ≥ 140

14,476

853

0.80 (0.70, 0.91)

6812

402

0.82 (0.66, 0.99)

DBP (mmHg)

 < 90

103,308

2324

0.77 (0.71, 0.83)

90,872

993

0.76 (0.67, 0.87)

 ≥ 90

12,458

668

0.83 (0.72, 0.96)

4534

171

0.83 (0.58, 1.17)

Smoker

 Now

4568

137

0.86 (0.73, 1.00)

27

1

__§

 Once

912

22

0.57 (0.39, 0.83)

22

2

__§

 Never

25,411

663

0.76 (0.65, 0.88)

20,684

248

__§

 Not recorded

84,875

2170

0.77 (0.72, 0.84)

73,512

912

 

Drinker

 Now

567

13

0.54 (0.30, 0.97)

29

0

__§

 Once

3312

89

0.74 (0.55, 1.00)

550

5

__§

 Never

27,012

720

0.79 (0.68, 0.91)

20,402

246

__§

 Not recorded

84,875

2170

0.78 (0.72, 0.85)

74,425

913

__§

Family history of diabetes

 No

114,136

2891

0.79 (0.73, 0.84)

92,705

1095

0.76 (0.67, 0.86)

 Yes

1630

101

0.63 (0.41, 0.96)

2701

69

0.71 (0.43, 1.18)

  1. Hazard ratios for diabetes were comparison of incident diabetes per 10 cm difference in height. The models were adjusted for age, weight, smoking, drinking, family history of diabetes, fasting blood glucose, low-density lipoprotein cholesterol, total cholesterol, triglyceride, alanine aminotransferase, aspartate transaminase, systolic blood pressure and diastolic blood pressure except the corresponding stratification variable.
  2. §The model failed because of the small sample size.
  3. *The results in the subgroup of subjects younger than 30 years may be unstable, with too many confounders adjusted and too few outcome events.
  4. BMI body mass index, FPG fasting plasma glucose, SBP systolic blood pressure, DBP diastolic blood pressure, HR hazard ratio, CI confidence interval.
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