Figure 4 | Scientific Reports

Figure 4

From: Rescue of murine hind limb ischemia via angiogenesis and lymphangiogenesis promoted by cellular communication network factor 2

Figure 4

Lymphatic vessels in the ischemic hind limb after treatment with CCN2. (a) Podoplanin-positive capillaries (lymphatic vessels) in myofibers of the ischemic hind limb in the control group (left) and the CCN2 group (right). The capillaries (stained in red) are indicated by white triangles. Original magnification, × 400; scale bar, 50 µm. (b) Change in density of podoplanin-positive capillaries per myofiber in the control group (n = 5; gray) and the CCN2 group (n = 5; light blue). The data are expressed as the mean ± standard error. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001. CCN2 cellular communication network factor 2, POD postoperative day.

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