Figure 6 | Scientific Reports

Figure 6

From: Hypobaric hypoxia induces iron mobilization from liver and spleen and increases serum iron via activation of ghrelin/GHSR1a/MAPK signalling pathway in mice

Figure 6

HH exposure of 7 days promoted TfR and Fpn expression in the liver and spleen of mice. (A,F) Western blotting analysis of HIF-1α, TfR and Fpn expression in the liver and spleen after 7 days of HH exposure. (B,G) Semiquantitative analysis of HIF-1α, TfR and Fpn expression in panels (A) and (F). (C,H) IHC images of TfR and Fpn expression in the liver and spleen after 7 days of HH exposure. (D–E,I–J) Semiquantitative analysis of TfR and Fpn expression in panels (C) and (H). Values are displayed as the mean ± SEM (n = 6 mice), * P < 0.05, ** P < 0.01, *** P < 0.001 versus the NN or indicated group.

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