Table 2 Enrichment scores of significant hallmark pathways between Subtype_O and Subtype_M samples in the training dataset.
From: Investigating subtypes of lung adenocarcinoma by oxidative stress and immunotherapy related genes
Pathway | Adjusted p-value | NES |
|---|---|---|
HALLMARK_MYC_TARGETS_V1 | 0.02 | 3.69 |
HALLMARK_E2F_TARGETS | 0.02 | 3.65 |
HALLMARK_OXIDATIVE_PHOSPHORYLATION | 0.02 | 3.32 |
HALLMARK_G2M_CHECKPOINT | 0.02 | 3.31 |
HALLMARK_MYC_TARGETS_V2 | 0.01 | 2.89 |
HALLMARK_MTORC1_SIGNALING | 0.03 | 2.61 |
HALLMARK_DNA_REPAIR | 0.02 | 2.59 |
HALLMARK_GLYCOLYSIS | 0.02 | 2.31 |
HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 0.02 | 2.17 |
HALLMARK_FATTY_ACID_METABOLISM | 0.02 | 1.82 |
HALLMARK_IL2_STAT5_SIGNALING |  < 0.01 |  − 2.23 |
HALLMARK_COAGULATION |  < 0.01 |  − 2.23 |
HALLMARK_COMPLEMENT |  < 0.01 |  − 2.36 |
HALLMARK_TNFA_SIGNALING_VIA_NFKB |  < 0.01 |  − 2.47 |
HALLMARK_KRAS_SIGNALING_UP |  < 0.01 |  − 2.47 |
HALLMARK_IL6_JAK_STAT3_SIGNALING |  < 0.01 |  − 2.49 |
HALLMARK_INTERFERON_GAMMA_RESPONSE |  < 0.01 |  − 2.57 |
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION |  < 0.01 |  − 2.58 |
HALLMARK_INFLAMMATORY_RESPONSE |  < 0.01 |  − 2.65 |
HALLMARK_ALLOGRAFT_REJECTION |  < 0.01 |  − 2.81 |
