Table 1 The integrative multiomic data analysis revealed genes, proteins and metabolites between the VAD-E and VAN groups with ARDS. The KEGG ID were cited from www.kegg.jp/kegg/kegg1.html.
KEGG ID | Pathway description | Genes | Pros | Metabolites |
|---|---|---|---|---|
rno04664 | Fc epsilon RI signaling pathway | RASK;FCERG | FCERG;RASK; | Leukotriene D4 |
rno04066 | HIF-1 signaling pathway | HMOX1;NOS2;TIMP1 | HMOX1;TIMP1;NOS2 | Oxoglutaric acid |
rno00480 | Glutathione metabolism | RIR2 | RIR2 | Spermidine;Dehydroascorbate |
rno00280 | Valine, leucine and isoleucine degradation | G3V7I5;ACDSB | G3V7I5;ACDSB | Ketoleucine |