Table 5 Researching results of CMAP.
CMAP name | Score | ID | Target | MOA |
|---|---|---|---|---|
Prostratin | 98.47 | BRD-K91145395 | PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCH, PRKCQ | PKC activator |
Flubendazole | 95.7 | BRD-K86003836 | TUBB | Tubulin inhibitor |
Ingenol | 95.63 | BRD-A52650764 | PRKCD, PRKCE | PKC activator |
KI-8751 | 95.54 | BRD-K47150025 | KDR | VEGFR inhibitor, KIT inhibitor, PDGFR receptor inhibitor |
KU-0063794 | − 95.14 | BRD-K67566344 | MTOR | MTOR inhibitor |
Dasatinib | − 95.57 | BRD-K49328571 | ABL1, FYN, LCK, SRC, KIT, YES1, BCR, EPHA2, LYN, PDGFRB, ABL2, BTK, DDR1, DDR2, PDGFRA, STAT5B | BCR-ABL kinase inhibitor, Ephrin inhibitor, KIT inhibitor, PDGFR receptor inhibitor, SRC inhibitor, Tyrosine kinase inhibitor |
