Table 2 Model-based odds ratios from mixed-effects logistic regression for positive immunoglobulin G serostatus against Borrelia burgdorferi s.l.

From: Seropositivity of Borrelia burgdorferi s.l. in Germany—an analysis across four German National Cohort (NAKO) study sites

 

Model 1 (n = 13,024)

Model 2 (n = 2878)

 

OR

95%-CI

p

OR

95%-CI

p

Age in 10-year increments

1.26

1.16–1.38

 < 0.001

1.29

1.07–1.54

0.009

Sex

 Female

Ref

Ref

Ref

Ref

Ref

Ref

 Male

2.54

2.05–3.13

 < 0.001

2.25

1.44–3.51

 < 0.001

Education (ISCED97)

 Low or ongoing

0.57

0.26–1.23

0.150

–

–

–

 Medium

Ref

Ref

Ref

–

–

–

 High

1.12

0.91–1.37

0.283

–

–

–

Migration background

 No

Ref

Ref

Ref

Ref

Ref

Ref

 Yes

0.56

0.41–0.78

0.001

0.28

0.11–0.69

0.006

Depression (PHQ-9)

 No

Ref

Ref

Ref

Ref

Ref

Ref

 Yes

0.80

0.51–1.25

0.327

0.85

0.31–2.37

0.761

Children within the household

 No

Ref

Ref

Ref

Ref

Ref

Ref

 Yes

0.77

0.58–1.02

0.067

1.16

0.68–2.00

0.587

Animals within household

 None

–

–

–

Ref

Ref

Ref

 Dog

–

–

–

0.63

0.31–1.28

0.206

 Cat

–

–

–

0.76

0.41–1.38

0.362

 Other

–

–

–

0.55

0.17–1.78

0.319

  1. OR = Odds Ratio; ISCED = International Standard Classification of Education; PHQ-9 = Patient Health Questionnaire 9; We defined seropositivity as positive or equivocal ELISA screening test with positive confirmatory line blot immunoassay; Model 1 contained all study participants; Model 2 contained only participants from the extended module, for which variables on animal contacts were available; in model 2, we excluded education as independent variable due to low person count in the low education group.
Back to article page