Figure 3

(a) In planta biodistribution after incubation with MES buffer for the metal and buffer control. (b) Biodistribution in leaf after incubation with MES buffer for the lipid nanoparticles formulated with DOTA(Gd). (c) Biodistribution in stem after incubation with MES buffer for the lipid nanoparticles with DOTA(Gd); (d) Biodistribution after incubation with MES buffer for the lipid nanoparticles formulated with a Gd-complex conjugated lipid and DOTA(Eu). In all cases, data are represented as mean ± SD (n = 3). All organs in the nanoparticle group were compared with the DOTA(Gd) group by Student’s t-test and results were labeled on the top of each column with “>” or “<” and p-value. ns not significant; *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001; ****p ≤ 0.0001.