Figure 6

Development and validation of the NETs-related signature. (A) The forest plot displaying the HR (95% CI) and p values of prognostic genes (top 10, according to p value). (B, C) 19 candidate genes were obtained by LASSO regression analysis. (D) The coefficients of the finally 10 genes in the signature. The Kaplan–Meier survival curves for BLCA patients stratified by the risk score in the TCGA training set (E), the TCGA validation set (F), the overall TCGA set (G), the external validation set (GSE3507 and GSE32894 merged) (H). ROC analysis at 1, 3, and 5 years of BLCA patients in the TCGA training set (I), the TCGA validation set (J), the overall TCGA set (K), and the external validation set (GSE3507 and GSE32894 merged) (L).