Figure 5

D-2-EPS inhibited tumor growth in vivo. The images of tumor (A), the growth curves of tumor volume (B), the immune-histochemical result of Ki67 of the tumor tissue (C), and the body weight (D) in the HT29 tumor xenograft model. (E) The HE-stained images of the heart, liver, spleen, lung, and kidney. (F) The protein levels of Fas, FasL. (G) The protein levels of caspases-8 and cleaved caspases-8. (H) The protein levels of caspase-3 and cleaved caspase-3. The blots were cut prior to hybridisation with antibodies. Values represent Mean ± SEM of the mean. Student's t-test, *P-value < 0.05, **P-value < 0.01, ***P-value < 0.001, ****P-value < 0.0001.