Figure 1

(A) Structures of some FDA-approved HDACis that present potent antiplasmodial activity and compounds 6a–8a, analogues of panobinostat. (B) Design of our urea-derived analogues of panobinostat. ZBG: zinc-binding group.

(A) Structures of some FDA-approved HDACis that present potent antiplasmodial activity and compounds 6a–8a, analogues of panobinostat. (B) Design of our urea-derived analogues of panobinostat. ZBG: zinc-binding group.