Table 1 Summary of parameters included in the PDE model (1), which has been used in many previous studies. Note that the diffusivity is not included in our model when operating on our mouse dataset since the work this data originates from13, and to which we compare our predictions to, did not include it. The diffusivity has been included in the sensitivity analysis however because it is included in many other studies.
Symbol | Name | Units | Tissue- vs. Particle- Specific |
|---|---|---|---|
\(\frac{L_p S}{V}\) | Transvascular Fluid Exchange Rate | 1/mmHg*s | Particle |
\(P_v\) | Microvascular Fluid Pressure | mmHg | Tissue |
\(\sigma \) | Reflection Coefficient | 1 | Particle |
K | Interstitial Hydraulic Conductivity | cm\(^2\)/mmHg*s | Particle |
f | Retardation Coefficient | 1 | Tissue |
\(k_d\) | Elimination Rate | 1/s | Tissue |
D | Diffusivity | cm\(^2\)/s | Particle |
