Table 3 Week 16: changes from baseline of the cardinal motor symptoms scores according to gender.

From: The effects of safinamide according to gender in Chinese parkinsonian patients

Parameter

Gender

Difference safinamide-placebo, LS mean (SE)

95% CI

p-value (entire cohort as compared to baseline)

Tremor

F

− 1.067 (0.487)

− 2.028, − 0.106

0.005

M

− 0.746 (0.412)

− 1.557, − 0.066

Bradykinesia

F

− 1.559 (0.707)

− 2.951, − 0.166

0.0013

M

− 1.446 (0.597)

− 2.622, − 0.270

Rigidity

F

− 0.984 (0.526)

− 2.020, 0.052

0.0016

M

− 1.227 (0.445)

− 2.104, − 0.348

PIGD

F

− 0.241 (0.382)

− 0.994, 0.512

0.1535

M

− 0.478 (0.324)

− 1.117, 0.160

  1. The p-value for the comparison of Safinamide versus Placebo was calculated irrespective of the gender because the treatment-by-gender interaction was not statistically significant. Significant values are in bold.
  2. LS Least Squares, SE Standard Error, CI Confidence Interval, PIGD Postural Instability Gait Disorder.