Figure 2
Circos plots of the five arrested equine embryos that contained chromosomal or genome-wide errors, with each circle representing the genome constitution per chromosome (1-X) of a single blastomere. Different colors represent different types of aneuploidies. Signatures of digynic trisomy across (almost all) chromosomes in Mare02_Embryo03 and Mare04_Embryo01 indicate digynic triploidy. Chromosomal errors of undefined parental origin (green) represent those that could be seen in the LogR plot, but were not confirmed by the parental haplarithm plots. Mare02_ Embryo02 was the only embryo that contained a normal, biparental diploid profile in all blastomeres and is not depicted. Lost blastomeres or blastomeres for which genetic analysis failed are not included, Also blastomere 5 of Mare01_Embryo02 was not included due to a low genome coverage and a complex aneuploid profile. Haplarithm plots of all blastomeres can be retrieved in Additional file 2, Fig. 1. In the middle of each circus plot, a picture of each embryo prior to dissociation is shown.
