Table 3 Molecular docking studies of LCDE phenolic compounds with NF-кB complex and their binding energy.

From: Antioxidant effects of phenolic compounds in through the distillation of Lonicera japonica & Chenpi extract and anti-inflammation on skin keratinocyte

Binding ligand

Amino acid residue interactions

Binding affinity score

Sweroside

ARG237, CYS149, GLU187, GLU233, PHE146, PRO147

− 6.6 kcal/mol

Isoliquiritin

ARG,232, ARG237, ARG239, ALA234, ASN240, CYS149, GLU233, LEU236

− 6.0 kcal/mol

Cardamonin

ARG232, ARG237, CYS149, GLU184, HIS183, LEU236

− 6.7 kcal/mol

Riboflavin

ARG232, ARG239, ASP194, CYS149, GLU184, LEU236, TYR227

− 6.9 kcal/mol

Arctigenin

ARG232, ARG237, CYS149, GLU115, GLU184, HIS193, ILE148, LEU236, PHE146, TYR227

− 7.9 kcal/mol

Back to article page