Table 1 Neurobehavioral assessment at week 4 and 9.
From: Long-term pulmonary and neurodevelopmental impairment in a fetal growth restriction rabbit model
|  | Postnatal days 21–25 | Postnatal days 56–60 | ||||
|---|---|---|---|---|---|---|
FGR | Control | p value | FGR | Control | p value | |
Open field test | ||||||
 Total distance (m) | 9.8 ± 3.5 | 13.5 ± 4.8 | 0.04 | 16.9 ± 9.0 | 10.5 ± 7.6 | 0.01 |
 Time in starting area (%) | 8.6 ± 7.6 | 14.8 ± 15.7 | 0.24 | 7.0 ± 10.7 | 6.2 ± 4.7 | 0.79 |
 Time in central area (%) | 9.7 ± 9.2 | 9.4 ± 7.9 | 0.93 | 17.7 ± 16.7 | 18.9 ± 25.3 | 0.89 |
 Time in corners (%) | 90.1 ± 9.2 | 90.5 ± 7.9 | 0.91 | 82.3 ± 16.7 | 81.0 ± 25.3 | 0.89 |
 Time self-grooming (%) | 47.2 ± 41.7 | 64.2 ± 65.5 | 0.49 | 19.0 ± 26.2 | 31.2 ± 56.2 | 0.52 |
 Escape attempts (n) | 2.7 ± 2.3 | 2.0 ± 1.9 | 0.43 | 2.9 ± 1.5 | 1.5 ± 1.7 | 0.03 |
 Times rearing (n) | 5.3 ± 4.9 | 4.6 ± 3.4 | 0.69 | 6.9 ± 7.6 | 3.2 ± 4.9 | 0.11 |
 Time lying down (s) |  |  |  | 0 (32.5) | 120 (185) | 0.02 |
Novel object recognition test | ||||||
 Discriminatory index | − 0.23 ± 0.59 | 0.73 ± 0.27 |  < 0.0001 | − 0.29 (0.34) | 0.7 (0.57) | 0.001 |
 T-maze test | ||||||
 Failure to choose (%) | 19.23 ± 18.13 | 35.71 ± 25.7 | 0.05 | 0 (43.5) | 0 (54.0) | 0.59 |
 Spontaneous alternation (%) | 80.62 ± 25.2 | 68.48 ± 31.64 | 0.25 | 55.5 ± 39 | 81.5 ± 29.8 | 0.07 |
