Table 1 Baseline characteristics in patients with or without poor outcome.

From: Cranial midline shift is a predictor of the clinical prognosis of acute cerebral infarction patients undergoing emergency endovascular treatment

Variables

mRS > 2 (n = 46, 56.1%)

mRS ≤ 2 (n = 36, 43.9%)

p

Sex (male)

25 (54.3)

25 (69.4)

0.164

Age (year)

57.5 [54.8–71.3]

60.0 [52.0–71.5]

0.581

Smoking

14 (30.4)

17 (47.2)

0.120

Alcohol consumption

13 (28.3)

14 (38.9)

0.309

Hypertension

23 (50)

26 (72.2)

0.042

Diabetes

11 (23.9)

10 (27.8)

0.691

Atrial fibrillation

20 (43.5)

10 (27.8)

0.143

Pre-stroke mRS score

0 [0-0]

0 [0-0]

0.009

Patients with sequelae of previous stroke

8 (17.4)

0 (0.0)

0.024

Baseline mRS score

4 [4-4]

4 [4-4]

0.917

Baseline NIHSS score

13.4 ± 3.9

12.6 ± 4.7

0.392

TOAST subtypes (large-artery atherosclerosis)

26 (56.5)

24 (66.7)

0.350

Intravenous thrombolytic therapy

8 (17.4)

13 (36.1)

0.054

Time between operation and onset (h)

10 [5.8–14.0]

9 [6.0–13.8]

0.940

Duration of operation (min)

137.5 [103.8–173.5]

126 [82.5–153.8]

0.174

anesthesia (general anesthesia)

28 (60.9)

20 (55.6)

0.628

Hemispheric infarct localization (right)

20 (43.5%)

14 (38.9%)

0.675

Large or medium vessel occlusions (large vessel)

36 (78.3%)

29 (80.6%)

0.799

Preoperative TICI-scores

0 [0–0]

0 [0–0]

0.783

Postoperative TICI-scores (≥ IIb)

41 (89.1)

35 (97.2)

0.332

Postoperative intracranial hemorrhage

21 (45.7%)

12 (33.3%)

0.259

hematoma growth

3 (6.5%)

0 (0.0%)

0.333

Decompression surgery required

9 (19.6)

1 (2.8)

0.049

Decompression surgery

4 (8.7%)

0 (0.0%)

0.194

Final infarction volume (ml)

77.88 [25.25–133.15]

14.81 [2.03–64.52]

 < 0.001

Time of postoperative CT review (h)

 Within 24 h

16.1 ± 4.88

16.2 ± 4.43

0.881

 Within 48 h

2 5 [17.75–38.0]

25 [18.25–38.0]

0.877

MLS location within 24 h

 Midbrain shift (mm)

0 [0–2.2]

0 [0–0]

 < 0.001

 Pineal gland shift (mm)

1.1 [0–2.65]

0 [0–0]

0.001

 Septum pellucidum shift (mm)

1.6 [0–4.2]

0 [0–0]

 < 0.001

 Cerebral falx shift (mm)

0 [0–2.725]

0 [0–0]

0.002

 MLS(max) (mm)

2.55 [0–4.2]

0 [0–0]

 < 0.001

MLS location within 48 h

 Midbrain shift (mm)

0 [0–2.3]

0 [0–0]

0.003

 Pineal gland shift (mm)

1.8 [0–3.425]

0 [0–0]

0.001

 Septum pellucidum shift (mm)

2.85 [0–4.375]

0 [0–0]

 < 0.001

 Cerebral falx shift (mm)

0 [0–3.4]

0 [0–0]

0.001

 MLS(max) (mm)

3.0 [0–5.0]

0 [0–1.6]

 < 0.001

  1. NIHSS, National Institute of Health stroke scale; CT, computed tomography; MLS, midline shift; MLS(max), maximal MLS for all MLS locations; ICA, internal carotid artery; MCA, middle cerebral artery; ACA, anterior cerebral artery; Large vessel, lumen diameters upper 2.0 mm: ICA, M1 segment of MCA; Medium vessel, lumen diameters between 0.75 and 2.0 mm: M2-3 segment of MCA and A2-A3 segment of ACA.
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