Figure 1
From: Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness

Periostin is highly expressed in recurrent ovarian cancer. (A) Gene expression microarray results for sixteen paired pOC and rOC tissues. The heatmap shows data from nine genes with > twofold differences in expression. (B) POSTN expression in each matched pOC–rOC pair. POSTN is increased in the rOC specimens for 11 of the 16 pairs (p = 0.015). Microarray assay was performed once per sample. (C) IHC staining using an anti-periostin antibody shows elevated periostin protein in rOC relative to pOC, with higher levels present in the stroma. Micrographs were taken at a total magnification of × 100.