Table 2 Univariate and multivariable interval censored proportional hazards model regression estimates of relative risk of being confirmed negative for ZIKV in plasma.

From: Detection and persistence of Zika virus in body fluids and associated factors: a prospective cohort study

Selected baseline factors

Univariate model

Multivariable model

Univariate HR (95% CI)

Chi-sq p value

Adjusted HR (95% CI)

Chi-sq p value

Sex

 Male

1.00

   

 Female

1.04 (0.79, 1.38)

0.78

  

Age group

 ≤ 35

1.00

   

 > 35

0.93 (0.72, 1.20)

0.58

  

Education level

 Secondary or lower

1.00

 

1.00

 

 Post-secondary

0.74 (0.55, 0.98)

0.03

0.72 (0.54, 0.96)

0.023

BMI category (kg/m2)

 Normal weight (18.5–24.99)

1.00

   

 Overweight or obese (≥ 25.0)

0.93 (0.70, 1.23)

0.61

  

Household members (excluding self)

 < 3

1.00

   

 ≥ 3

1.09 (0.82, 1.44)

0.56

  

Fever today or past 30 days

 (Yes vs No)

1.29 (0.91, 1.81)

0.15

  

Rash today or past 30 days

 (Yes vs No)

1.90 (0.61, 5.97)

0.27

  

Pruritus today or past 30 days

 (Yes vs No)

1.26 (0.74, 2.16)

0.39

  

Non purulent conjunctivitis today or past 30 days

 (Yes vs No)

1.18 (0.89, 1.57)

0.26

  

Joint pain today or past 30 days

 (Yes vs No)

1.33 (0.96, 1.84)

0.09

1.38 (0.99, 1.91)

0.06

Periarticular edema today or past 30 days

 (Yes vs No)

1.19 (0.91, 1.57)

0.21

  

Yellow fever vaccination?

 (Yes vs No)

0.99 (0.61, 1.60)

0.97

  
  1. HR > 1 implies a higher probability of being confirmed ZIKV RNA negative in plasma (lower likelihood of ZIKV persistence); HR < 1 implies a lower probability of being confirmed ZIKV RNA negative in plasma (increased likelihood of ZIKV persistence).
  2. ZIKV Zika virus, BMI body mass index, HR hazard ratio, CI confidence interval.