Table 6 Univariate and multivariable interval censored proportional hazards model regression estimates of relative risk of being confirmed negative for ZIKV in rectal swabs.
Selected baseline factors | Univariate model | Multivariable model | ||
|---|---|---|---|---|
Univariate HR (95% CI) | Chi-sq p value | Adjusted HR (95% CI) | Chi-sq p value | |
Sex | – | – | ||
Male | 1.00 | |||
Female | 1.056 (0.80, 1.39) | 0.70 | ||
Age group | ||||
≤ 35 | 1.00 | 1.00 | ||
> 35 | 1.56 (1.20, 2.01) | 0.0008 | 0.0005 | |
Education level | ||||
Secondary or lower | 1.00 | – | – | |
Post-secondary | 0.90 (0.68, 1.18) | 0.45 | ||
BMI category (kg/m2) | – | – | ||
Normal weight (18.5–24.99) | 1.00 | |||
Overweight or obese (≥ 25.0) | 0.96 (0.73, 1.27) | 0.79 | ||
Household members (excluding self) | – | – | ||
< 3 | 1.00 | |||
≥ 3 | 0.98 (0.74, 1.29) | 0.89 | ||
Fever today or past 30 days | – | – | ||
(Yes vs No) | 1.11 (0.78, 1.58) | 0.55 | ||
Rash today or past 30 days | – | – | ||
(Yes vs No) | 2.12 (0.67, 6.68) | 0.20 | ||
Pruritus today or past 30 days | – | – | ||
(Yes vs No) | 1.07 (0.63, 1.84) | 0.80 | ||
Non purulent conjunctivitis today or past 30 days | – | – | ||
(Yes vs No) | 1.11 (0.83, 1.47) | 0.49 | ||
Joint pain today or past 30 days | – | – | ||
(Yes vs No) | 0.98 (0.70, 1.35) | 0.88 | ||
Periarticular edema today or past 30 days | – | – | ||
(Yes vs No) | 1.07 (0.81, 1.41) | 0.63 | ||
Yellow fever vaccination? | ||||
(Yes vs No) | 1.20 (0.73, 1.99) | 0.47 | 0.09 | |
Interaction (Yellow fever vaccination*Age group) | 0.0054 | |||
Stratified for yellow fever vaccinated = Yes | ||||
Age > 35 (vs age ≤ 35) | 1.37 (1.01, 1.87) | |||
Stratified for yellow fever vaccinated = No | ||||
Age > 35 (vs age ≤ 35) | 6.46 (2.25, 18.5) | |||
Stratified for age group ≤ 35 | ||||
Vaccinated for yellow fever (vs not vaxed) | 1.83 (0.90, 3.71) | |||
Stratified for age group > 35 | ||||
Vaccinated for yellow fever (vs not vaxed) | 0.39 (0.17, 0.89) | |||
