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Figure 1

From: Solving the mystery of the FMC63-CD19 affinity

Figure 1

Summary of reported KD values for the interaction of the FMC63-scFv with CD19 and potential artefacts in steady-state binding assays. (A) Overview of published FMC63-scFv affinities. (B) Table summarizing publications describing the interaction of the FMC63-scFv with CD19, including the source and architecture of the two interaction partners as well as the applied method to determine the KD value; n.a., not available. (C–E) Illustrations explaining common artefacts and pitfalls when determining affinities by steady-state analysis.

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